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Prednisone tablets belong to the pharmacological group of oral glucocorticosteroids for oral use. They have a pronounced anti-inflammatory pharmacological effect and are used for various systemic pathologies, primarily associated with an autoimmune pathological process.

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Indications for use

To date, there are a significant number of medical indications for the use of Prednisone tablets, these include:

  • Endocrinological pathology – congenital adrenal hypoplasia (adrenogenital syndrome), primary or secondary insufficiency of the adrenal cortex, as a replacement therapy before surgery in patients with adrenal insufficiency, autoimmune thyroiditis (inflammation of the thyroid gland due to the production of antibodies by the immune system to its cells).
  • Severe allergic pathology, contact dermatitis, serum sickness, anaphylactic shock, Quincke’s angioedema, allergic rhinitis.
  • Rheumatic systemic diseases in which connective tissue is affected due to an autoimmune process.
  • Skin diseases – severe erythema multiforme, severe psoriasis, eczema, pemphigus, fungal skin lesions, seborrheic, exfoliative dermatitis, bullous dermatitis herpetiformis, pemphigoid.
  • Pathology of the blood system – autoimmune hemolytic anemia, hemolysis, congenital aplastic anemia, Werlhof’s disease (idiopathic thrombocytopenic purpura).
  • Chronic hepatitis in the active stage, alcoholic liver damage.
  • Bursitis in the stage of acute and subacute course, acute tendovaginitis, epicondylitis, osteoarthritis, which develops as a result of trauma.
  • Breast cancer in women, prostate cancer in men, multiple myeloma, various types of lymphomas, acute and chronic leukemia.
  • Tuberculous meningitis, myasthenia gravis, multiple sclerosis in the active stage.
  • A severe form of sluggish posterior uveitis in the active stage, sympathetic ophthalmopathy, optic neuritis.
  • Pericarditis.
  • Berylliosis, chronic emphysema, bronchial asthma, symptomatic sarcoidosis, disseminated pulmonary tuberculosis.

Prednisone online also prevent tissue rejection after organ transplantation in transplantology.

Contraindications for use

Since Deltasone is used mainly for the treatment of severe pathology, the list of contraindications is small:

  • Hypersensitivity to the active substance of the drug.
  • The development of severe systemic fungal infections, in which additional suppression of the immune system leads to their progression.

Before prescribing Prednisone 20mg, the doctor must make sure that there are no contraindications.

Dosage and method of application

Prednisone cheap medication are for oral use. They are used orally, usually after meals, 1 time per day, which is associated with the daily rhythm of secretion of glucocorticosteroids by the adrenal cortex (sometimes, if necessary, the frequency of taking tablets can be increased).

The dose is set by the doctor individually, which depends on the type, severity, and characteristics of the course of the pathological process in the patient’s body. After reaching the desired therapeutic effect, the dose is gradually reduced until it is maintained. The average daily dose for an adult varies between 10 – 40 mg. The maximum daily dose should not exceed 40mg.

Side effects

With a short-term intake of buy Prednisone 20mg, side effects develop extremely rarely. With longer use of Deltasone, the development of negative reactions from various organs and systems is possible:

  • Steroid ulcer of the stomach or duodenum, periodic nausea, vomiting, increased appetite, inflammation of the pancreas, esophagus, indigestion, flatulence.
  • Increased intracranial pressure, which is accompanied by a syndrome of congestive optic disc, sleep disturbances, convulsions, severe dizziness, headache, fainting.
  • Adrenal insufficiency, suppression of the growth process in children, hyperglycemia, menstrual irregularities in women, the manifestation of latent diabetes mellitus, hirsutism.
  • Muscle weakness, osteoporosis, which is the cause of subsequent pathological fractures.
  • Skin atrophy, striae on it, deterioration of wound healing, erythema, hyperhidrosis, acne, petechial hemorrhages on the skin.
  • Cataract, an increase in intraocular pressure, due to which glaucoma subsequently develops, exophthalmos.
  • Symptoms of psychosis may appear, especially in the first 2 weeks after the start of taking Prednisone drug, it develops more often in women and in persons with systemic lupus erythematosus.
  • Negative nitrogen balance in the body, which is caused by increased destruction of proteins, an increase in body weight.
  • Decrease in the number of leukocytes (leukopenia), platelets (thrombopenia), an increase in the level of calcium in the blood, urine, an increase in the level of triglycerides,total cholesterol, as well as low and very low-density lipoproteins.
  • Allergic reactions.

In the event of the development of side effects, the doctor decides on the abolition of Prednisone tablets individually, depending on their type, nature, and severity.

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